complement component 9

complement component 9 - Names and Identifiers

Name	4-fluoro-2-(trifluoromethyl)phenylacetic acid
Synonyms	RARECHEM AL BO 0505 complement component 9 (2-Trifluoromethyl-4-fluorophenyl)acetic acid 4-fluoro-2-(trifluoromethyl)phenylacetic acid 4-FLUORO-3-(TRIFLUOROMETHYL)PHENYLACETIC ACID 2-(4-Fluoro-2-(trifluoromethyl)phenyl)acetic acid 2-(Carboxymethyl)-5-fluorobenzotrifluoride, 2-(Carboxymethyl)-alpha,alpha,alpha,5-tetrafluorotoluene
CAS	195447-80-4
InChI	InChI=1/C9H6F4O2/c10-6-2-1-5(3-8(14)15)7(4-6)9(11,12)13/h1-2,4H,3H2,(H,14,15)

complement component 9 - Physico-chemical Properties

Molecular Formula	C9H6F4O2
Molar Mass	222.14
Density	1.436
Melting Point	51-55°C(lit.)
Boling Point	248℃
Flash Point	>230°F
Vapor Presure	0.0134mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.459
MDL	MFCD00061189

complement component 9 - Risk and Safety

Risk Codes	R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36/37 - Wear suitable protective clothing and gloves.
WGK Germany	3
Hazard Class	IRRITANT

complement component 9 - Introduction

4-fluoro-2-(trifluoromethyl)phenylacetic acid is an organic compound. Its molecular formula is C9H5F4O2, structural formula is CF3C6H4CH2COOH. The following is a description of its nature, use, preparation and safety information:

Nature:
4-fluoro-2-(trifluoromethyl)phenylacetic acid is a colorless to pale yellow crystalline solid. It is stable at room temperature and is not volatile. It has low solubility in water and better solubility in organic solvents. It is a weak acid that can react with a base to form the corresponding salt.

Use:
4-fluoro-2-(trifluoromethyl)phenylacetic acid is commonly used as an important reagent in drug synthesis and organic synthesis. It can act as an acylating agent, carboxylating agent, amidating agent, etc. It can be used in the synthesis of esters, amides, acylates and other active molecules in pharmaceutical research.

Method:
Generally, 4-fluoro-2-(trifluoromethyl)phenylacetic acid can be prepared by fluorination, diazotization, acid treatment and other steps of trifluorotoluene. There are many specific preparation methods, and the detailed steps can refer to the relevant organic synthesis literature.

Safety Information:
4-fluoro-2-(trifluoromethyl)phenylacetic acid should follow the safe operation regulations of Organic Synthesis Laboratory in operation. It is irritating to the eyes and skin, contact it should be washed immediately with plenty of water. At the same time, it should be stored in a dry, ventilated place, away from heat and fire sources. Wear protective glasses, gloves and protective clothing during use. If the substance is inhaled or ingested, seek medical advice immediately.

Last Update：2024-04-09 21:11:58